Voprosy meditsinskoi khimii (ISSN 0042-8809)

Oxidative phosphorylation of Krebs cycle substrates in experimental treatment of enterocolitis with cytochrome c

   
Khadzhiev K.Kh., Chirko I.G.
PubMed Id: 6256954
Year: 1980 vol: 26  issue:2  pages: 154-157
Abstract: After administration of exogenous cytochrome c into rats with enterocolitis, caused by salmonellae, tissue respiration and oxidative phosphorylation in presence of succinic, alpha-ketoglutaric, pyruvic and oxaloacetic acids were increased in the liver tissue. Treatment with cytochrome c produced a positive effect on the general state of an organism, led to disappearance of macroscopic alterations in mucosa of small intestine. The data obtained suggest that cytochrome c possesses the positive therapeutic effects in enterocolitis caused by salmonellae.
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Reference: Khadzhiev K.Kh., Chirko I.G., Oxidative phosphorylation of Krebs cycle substrates in experimental treatment of enterocolitis with cytochrome c, Voprosy meditsinskoi khimii, 1980, vol: 26(2), 154-157.
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