Voprosy meditsinskoi khimii (ISSN 0042-8809)

Concentration of free and esterified cholecalciferol in the tissues of rats with hypervitaminosis D

   
Petrova E.A., Lazareva N.P., Khudadov G.D.
PubMed Id: 6256958
Year: 1980 vol: 26  issue:3  pages: 325-328
Abstract: Within 4 hrs after intravenous administration into rats of cholecalciferol maximal concentration of the compound, which was increased depending on the dose used, was found in liver tissue, within 24 hrs--in kidney. Increase in cholecalciferol doses led to an increase in the ratio of the esterified compound to its free form. Content of the esterified cholecalciferol reached the highest level in kidney within 4 hrs and 24 hrs after administration of all the doses of cholecalciferol studied.
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Reference: Petrova E.A., Lazareva N.P., Khudadov G.D., Concentration of free and esterified cholecalciferol in the tissues of rats with hypervitaminosis D, Voprosy meditsinskoi khimii, 1980, vol: 26(3), 325-328.
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