Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of dysentery endotoxin on the histamine and serotonin concentration in the mucosa of the small intestine

   
Shenkman B.Z.
PubMed Id: 7006204
Year: 1980 vol: 26  issue:3  pages: 351-354
Abstract: An increase in histamine content and a decrease in serotonin concentration occurred in mucosa of mouse large intestine in dynamics of dysenteric intoxication. The content of serotonin was more dependent on the endotoxin dose and duration of its action of these biogenic amines in normal state was altered under the pathological conditions. The impairments in metabolism of biogenic amines in response to dysenteric intoxication were reduced after administration of tryptophane and pyridoxine suggesting the reversibility of these impairments.
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Reference: Shenkman B.Z., Effect of dysentery endotoxin on the histamine and serotonin concentration in the mucosa of the small intestine, Voprosy meditsinskoi khimii, 1980, vol: 26(3), 351-354.
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