Voprosy meditsinskoi khimii (ISSN 0042-8809)

Biosynthesis of rat spleen DNA following stimulation of hematopoiesis with phenylhydrazine

   
Rusinova G.G.
PubMed Id: 7456380
Year: 1980 vol: 26  issue:4  pages: 446-449
Abstract: 3H-Thymidine incorporation into DNA of rat spleen was increased 11-fold, as compared with controls, within the fourth day of the experiment involving two daily administrations of phenylhydrazine. HCl into the animals at a dose of 3 mg/100 g of body mass. Administration of 1 mCi of 3H-thymidine per 100 g of body mass enabled to obtain 3H-DHA from rat spleen with specific radioactivity of 30-40 x 10(6) imp/min per 1 mg of the biopolymer.
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Reference: Rusinova G.G., Biosynthesis of rat spleen DNA following stimulation of hematopoiesis with phenylhydrazine, Voprosy meditsinskoi khimii, 1980, vol: 26(4), 446-449.
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