Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of furan compounds on lipid peroxidation in rat liver

   
Danilov V.B., Vinokurova T.I., Tarasov V.V., Zavgorodniaia S.V.
PubMed Id: 7456384
Year: 1980 vol: 26  issue:4  pages: 470-472
Abstract: Effect of some furan compounds--monofurfurilidene acetone (MFA), difurfurilidene acetone (DIFA), furyl alcohol (Fal) and furfurol (Fl)--on peroxidation of unsaturated fatty acids in lipids was studied in subcellular organelles of rat liver cells in vitro. By the rate of inhibition of lipid peroxidation the substances studied were arranged as follows: DIFA--100%, Fal--65%, Fl--27% and MFA--1-2%. The furan derivatives at the concentration 10(-2) M effectively inhibited the lipid peroxidation in subcellular organelles, especially in mitochondrial and microsomal fractions.
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Reference: Danilov V.B., Vinokurova T.I., Tarasov V.V., Zavgorodniaia S.V., Effect of furan compounds on lipid peroxidation in rat liver, Voprosy meditsinskoi khimii, 1980, vol: 26(4), 470-472.
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