Voprosy meditsinskoi khimii (ISSN 0042-8809)

Combination of lipid gas and thin-layer chromatography in the diagnosis of functional hepatic failure

   
Orgel' M.Ia., Bondarenko B.N., Sokol A.S., Plenov N.N., Shalimov S.A.
PubMed Id: 7456399
Year: 1980 vol: 26  issue:4  pages: 548-552
Abstract: Gas chromatography of total lipids from blood serum exhibits about 40% error in diagnosis of liver functional insufficiency. Combination of gas chromatography with quantitative thin-layer chromatography and subsequent gas chromatographic analysis of the lipid fractions obtained enabled to increase by 25% the efficiency of diagnoses not only of icteric but also of non-icteric forms of liver functional insufficiency. Simultaneous gas- thin-layer chromatographic analysis of total lipids will apparently improve the differential diagnosis of diseases accompanied by liver functional insufficiency; it permits also to study pathogenesis of impairments in lipid metabolism under conditions of liver functional insufficiency and of other pathologies.
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Reference: Orgel' M.Ia., Bondarenko B.N., Sokol A.S., Plenov N.N., Shalimov S.A., Combination of lipid gas and thin-layer chromatography in the diagnosis of functional hepatic failure, Voprosy meditsinskoi khimii, 1980, vol: 26(4), 548-552.
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