Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of nitrofuran derivatives on the oxygen consumption by rat liver mitochondria

   
Kozhanova S.V., Basenova A.T., Buzurbaev G.G.
PubMed Id: 7423873
Year: 1980 vol: 26  issue:5  pages: 605-608
Abstract: Utilization of oxygen in rat liver mitochondria was studied using two nitrofuran derivatives 5-nitro-2-furaldehyde semicarbazone (furacin) and soluble derivative of nitrofuran--M-106-P. The substances at 10(-3) M concentration increased O2 consumption in mitochondria with simultaneous decrease in the respiratory control. After blocking of respiration with KCN, antimycine, rhothenone, the nitrofurans stimulated O2 consumption in mitochondria up to 30% as compared with controls.
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Reference: Kozhanova S.V., Basenova A.T., Buzurbaev G.G., Effect of nitrofuran derivatives on the oxygen consumption by rat liver mitochondria, Voprosy meditsinskoi khimii, 1980, vol: 26(5), 605-608.
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