Voprosy meditsinskoi khimii (ISSN 0042-8809)

Comparative studies of 35S-hemineurine and 35S-thiamine distribution and binding by proteins in the neural structures of the rat brain

   
Filippova L.B., Rozanov A.Ya.
PubMed Id: 7423880
Year: 1980 vol: 26  issue:5  pages: 643-646
Abstract: 35S-Hemineurine penetrated across the blood-brain barrier more rapidly than 35S-thiamin within the first 30 min after intravenous administration. Within 24 hrs content of 35S-thiamin in the neurones exceeded by 34% its concentration in glia and by 200% -- in myelin fraction. 35S-Hemineurine was bound slightly with brain proteins as compared with thiamin and it was removed at the higher rate from brain regions and subcellular structures.
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Reference: Filippova L.B., Rozanov A.Ya., Comparative studies of 35S-hemineurine and 35S-thiamine distribution and binding by proteins in the neural structures of the rat brain, Voprosy meditsinskoi khimii, 1980, vol: 26(5), 643-646.
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