Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of a single administration of hydrocortisone within various periods of a day on the incorporation of the labeled precursor into nuclear proteins of intact rat liver

   
Savina M.I., Spivak S.M.
PubMed Id: 6792780
Year: 1981 vol: 27  issue:3  pages: 352-355
Abstract: A single administration of hydrocortisone within various periods of a day led to distinct and dissimilar alterations in distribution of 14C-lysine in erythrocytes, blood plasma and in liver tissue homogenates. The hydrocortisone injection also changed the synthesis of nuclear proteins, especially during the day time. The ability of cell-targets to accept the hormonal signal depended on the functional state of cell chromatin, which is responsible for realization of the signal effect.
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Reference: Savina M.I., Spivak S.M., Effect of a single administration of hydrocortisone within various periods of a day on the incorporation of the labeled precursor into nuclear proteins of intact rat liver, Voprosy meditsinskoi khimii, 1981, vol: 27(3), 352-355.
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