Voprosy meditsinskoi khimii (ISSN 0042-8809)

Retinol receptors in rat retina: various molecular forms

   
Pokrovskiĭ B.V., Shabanova M.E., Mitsner B.I.
PubMed Id: 7197081
Year: 1981 vol: 27  issue:3  pages: 392-397
Abstract: Analysis of vitamin A-binding components in a soluble fraction of rat retina was carried out using gel filtration and gradient ultracentrifugation. Use of a wide range of concentrations of labelled retinol (6.10-8 = 2. 10-5 M) enabled to detect both high and low molecular forms of the binding components of retina. High molecular components (5S, 7S) were mainly found at physiological concentrations of retinol and at the higher (10-6=10-5 M) concentrations. Low molecular mass receptor (2S) prevailed under conditions of loading of the soluble fraction with subphysiological (nmol) concentrations of retinol.
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Reference: Pokrovskiĭ B.V., Shabanova M.E., Mitsner B.I., Retinol receptors in rat retina: various molecular forms, Voprosy meditsinskoi khimii, 1981, vol: 27(3), 392-397.
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