Voprosy meditsinskoi khimii (ISSN 0042-8809)

Several approaches to purifying rat liver G2-chalone

   
Rodionov V.M., Kuz'micheva N.A., Pospelova A.V., Pleskova M.V.
PubMed Id: 6170167
Year: 1981 vol: 27  issue:4  pages: 569-572
Abstract: An attempt was made to isolate the liver tissue chalone blocking the transition of hepatocytes from G2 period of the cell cycle into mitosis/g2-chalone/. The purification was carried out using gel filtration through Sephadex G-75 and hydroxyapatite chromatography as well as by means of ultrafiltration through Diaflo membranes XM-300, XM-100 and PM-10. The biologically active preparation, obtained by these two procedures, was purified 100-fold. Molecular mass of G2 chalone was apparently less then 10,000; it penetrated through PM-10 membrane. The chalone appears to form complexes with high molecular carriers.
Download PDF:
Reference: Rodionov V.M., Kuz'micheva N.A., Pospelova A.V., Pleskova M.V., Several approaches to purifying rat liver G2-chalone, Voprosy meditsinskoi khimii, 1981, vol: 27(4), 569-572.
References
 1985(Vol:31)
 1984(Vol:30)
 1983(Vol:29)
 1982(Vol:28)
 1981(Vol:27)
 1980(Vol:26)
 1979(Vol:25)
 1978(Vol:24)
 1977(Vol:23)
 1976(Vol:22)