Voprosy meditsinskoi khimii (ISSN 0042-8809)

Total and neutral lipid content in mouse myocardial tissue as affected by typhoid endotoxin

   
Muzhuchenko A.V., Khardina G.A.
PubMed Id: 7314583
Year: 1981 vol: 27  issue:5  pages: 650-654
Abstract: Content of total lipids was markedly increased in mice myocardium after intraperitoneal administration of typhoid endotoxins, isolated as described by Bouivene (preparation B) and by Westphal (preparation W). Concentrations of triacylglycerols, free fatty acids, esterified and free cholesterol were mainly altered. Mono- and diacylglycerols occurred in myocardial neutral lipids within 24 hrs after the treatment with LD100 of endotoxins and within 36 hrs after the treatment with LD50 of endotoxins. The alterations observed tended to disappear within 5 days after administration of the preparation "W" LD50. Possible effects of typhoid endotoxin on lipid metabolism in myocardium are discussed.
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Reference: Muzhuchenko A.V., Khardina G.A., Total and neutral lipid content in mouse myocardial tissue as affected by typhoid endotoxin, Voprosy meditsinskoi khimii, 1981, vol: 27(5), 650-654.
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