Voprosy meditsinskoi khimii (ISSN 0042-8809)

ATP, ADP and AMP content in the low-temperature preservation of lymphoid cells

   
Gordienko A.D., Fedets O.I.
PubMed Id: 7336648
Year: 1981 vol: 27  issue:6  pages: 746-749
Abstract: As compared with ATP and ADP concentration in native lymphocytes, content of ATP was decreased down to 26.3% and 35.1% and of ADP--37.0% and 44.4% in the cell preparations after conservation in mixtures containing 10% PEO-400 and dimethyl-sulfoxide (DMSO). AMP was not found in the lymphocytes when both PEO-400 and DMSO were used. Mechanisms responsible for instability of lymphocyte adenine nucleotides under conditions of low temperature conservation are discussed.
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Reference: Gordienko A.D., Fedets O.I., ATP, ADP and AMP content in the low-temperature preservation of lymphoid cells, Voprosy meditsinskoi khimii, 1981, vol: 27(6), 746-749.
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