Voprosy meditsinskoi khimii (ISSN 0042-8809)

Functioning of mucosal mitochondria of the small intestine in exposure of rats to high environmental temperature

   
Musaev K.N., Almatov K.T., Rakhimov M.M., Akhmedov R.R.
PubMed Id: 7336652
Year: 1981 vol: 27  issue:6  pages: 763-769
Abstract: Oxidative phosphorylation in mitochondria of small intestinal mucosa was studied after repeated overheating of rats. The hyperthermia affected the respiratory chains of mitochondrial membranes, facilitating the penetration of ADP, succinate, alpha-ketoglutarate and NADH across the membranes. Under these conditions thermostability of the respiratory chain multienzyme system was decreased and the rate of exogenous cytochrome c incorporation into mitochondrial membranes was altered. In the mitochondrial membranes from small intestinal mucosa there was noted development of latent impairments, the reversibility of which depended on the intensity and duration of hyperthermia.
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Reference: Musaev K.N., Almatov K.T., Rakhimov M.M., Akhmedov R.R., Functioning of mucosal mitochondria of the small intestine in exposure of rats to high environmental temperature, Voprosy meditsinskoi khimii, 1981, vol: 27(6), 763-769.
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