Voprosy meditsinskoi khimii (ISSN 0042-8809)

Membrane-bound sialoglycoproteins of the rat liver as affected by the combined action of benz(a)pyrene and sulfur dioxide

   
Merkur'eva R.V., Bushinskaia L.I., Skvortsova N.I., Dolinskaia S.I., Shaternikova I.S.
PubMed Id: 6278760
Year: 1981 vol: 27  issue:6  pages: 791-794
Abstract: Simultaneous effect of benz(a)pyrene and sulphurous gas was accompanied by distinct alteration in metabolism of sialoglycoproteins in liver tissue; at the time N-acetylneuraminic acid was redistributed in liver subcellular organelles (mitochondria, lysosomes and endoplasmic reticulum) as well as cytochromes P-450 and b5 were induced in liver microsomes. The alterations observed appear to play a definite role in manifestation of the unfavourable effect in combined action of the carcinogen and chemical contaminations of environments.
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Reference: Merkur'eva R.V., Bushinskaia L.I., Skvortsova N.I., Dolinskaia S.I., Shaternikova I.S., Membrane-bound sialoglycoproteins of the rat liver as affected by the combined action of benz(a)pyrene and sulfur dioxide, Voprosy meditsinskoi khimii, 1981, vol: 27(6), 791-794.
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