Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of remantadine, ribavirin and their combinations on the protein synthesis of influenza virus A in a cell culture

   
L'vov N.D., Pushkarskaia N.L., Galegov G.A.
PubMed Id: 7336658
Year: 1981 vol: 27  issue:6  pages: 820-823
Abstract: Simultaneous use of ribavirin (I-beta-D-ribofuranosyl-1,2,4-triazol-3-carboxamide and rimantadine (alpha-methyl-I-adamantane methylamine HCL) was shown to effect most distinctly on protein synthesis in influenza virus A in the system studied as compared with the separate action of each of the drugs. Ribavirine inhibited the protein synthesis in rimantadine-resistant strain of influenza virus A.
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Reference: L'vov N.D., Pushkarskaia N.L., Galegov G.A., Effect of remantadine, ribavirin and their combinations on the protein synthesis of influenza virus A in a cell culture, Voprosy meditsinskoi khimii, 1981, vol: 27(6), 820-823.
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