Voprosy meditsinskoi khimii (ISSN 0042-8809)

Changes in the content of opiate-like substances in auricular electroacupuncture anesthesia of rats

   
Bragin E.O., Dionne R.R., Ng L.L., Moody T.T., Pert K.K.
PubMed Id: 7113049
Year: 1982 vol: 28  issue:4  pages: 102-105
Abstract: It was shown that auricular electro-acupuncture in rats, sufficient to induce analgesia, resulted in a significant increase of endorphins in cerebro-spinal fluid with a concomitant decrease in the basomedial hypothalamus and medial thalamus of beta-endorphin-like immunoreactivity as well as endorphin-like radioreceptor activity. In addition, the radioreceptor assay also revealed a decrease of endorphin-like radioreceptor activity in the periaqueductul gray matter. plasma levels of endorphins were not altered. Cerebro-spinal fluid contained only endogenous opiate ligand material with enkephalin-like molecular weight.
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Reference: Bragin E.O., Dionne R.R., Ng L.L., Moody T.T., Pert K.K., Changes in the content of opiate-like substances in auricular electroacupuncture anesthesia of rats, Voprosy meditsinskoi khimii, 1982, vol: 28(4), 102-105.
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