Voprosy meditsinskoi khimii (ISSN 0042-8809)

Metabolic consequences of kidney normothermic ischemia

   
Shepotinovskiĭ V.I., Makashinovich Z.I., Kopeliovich G.A.
PubMed Id: 6858034
Year: 1983 vol: 29  issue:2  pages: 44-47
Abstract: Normothermic ischemia of kidney within 1 hr caused critical impairments in metabolic reactions of nephrons. Activities of glucose-6-phosphate and lactate dehydrogenases in erythrocytes may characterize the functional state of kidney tissue in ischemia. Amount of 2,3-glucose diphosphate in erythrocytes correlated with the diuresis level. Kidney tissue ischemia led to alteration in the ratio of young and old erythrocyte populations in circulation. Alterations in activity of glucose-6-phosphate and lactate dehydrogenases in urine occurred due to both an increase in kidney clearance and the impairment of kidney tissue.
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Reference: Shepotinovskiĭ V.I., Makashinovich Z.I., Kopeliovich G.A., Metabolic consequences of kidney normothermic ischemia, Voprosy meditsinskoi khimii, 1983, vol: 29(2), 44-47.
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