Voprosy meditsinskoi khimii (ISSN 0042-8809)

Alpha-2-globulins of blood in experimental burns

Movshev B.E., Averchenko V.I.
PubMed Id: 6190315
Year: 1983 vol: 29  issue:2  pages: 64-69
Abstract: Complex physico-chemical procedures for separation and analysis of protein composition during the separation steps showed that alpha-2-globulins from blood serum of rats with thermic burns differed from the globulins of normal blood serum either in absolute and relative increase in their content or qualitative features: increase in electrophoretic mobility, conformational changes leading to increase in compactness at the slightly acid pH, increase in affinity to anion exchange resin, atypical reactions with a precipitant (rivanol), increase in the rate of dissociation into subunits. The major part of alpha-2-globulins in burns constituted alpha-2-lipoprotein and alpha-2-macroglobulin which were separated with minimal cross-contamination.
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Reference: Movshev B.E., Averchenko V.I., Alpha-2-globulins of blood in experimental burns, Voprosy meditsinskoi khimii, 1983, vol: 29(2), 64-69.