Voprosy meditsinskoi khimii (ISSN 0042-8809)

Biogenic monoamines and their precursors in rats with spontaneous arterial hypertension

   
Kaliman P.A., Sergienko N.G., Luchko N.A., Brovina N.N.
PubMed Id: 6858037
Year: 1983 vol: 29  issue:2  pages: 69-73
Abstract: Content of tryptophane, tyrosine, serotonin, noradrenaline, adrenaline and dopamine was studied in blood serum and various brain regions of rats with genetically determined spontaneous form of hypertension. The arterial pressure of these animals was shown to depend on activity of noradrenaline-, serotonin- and dopaminergic systems of brain. Oppositely directed alterations in content of dopamine and noradrenaline were observed in various brain regions apparently as a result of changes in activity of the enzymes involved in the amines synthesis and degradation.
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Reference: Kaliman P.A., Sergienko N.G., Luchko N.A., Brovina N.N., Biogenic monoamines and their precursors in rats with spontaneous arterial hypertension, Voprosy meditsinskoi khimii, 1983, vol: 29(2), 69-73.
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