Voprosy meditsinskoi khimii (ISSN 0042-8809)

Transketolase activity and thiamine diphosphate content in oncological patients

   
Trebukhina R.V., Tumanov V.N., Avdeĭchik L.A., Bobko I.N., Tsabenko I.I.
PubMed Id: 6649520
Year: 1983 vol: 29  issue:5  pages: 100-103
Abstract: In blood of patients with cancer of stomach and mammary gland total thiamin content was measured by means of fluorimetric procedure, thiamindiphosphate (TDP)--by an enzymatic method, activity of transketolase was estimated in presence or in absence of TDP. Concentration of total thiamin in blood of healthy persons was 7.65 +/- 0.40 micrograms/100 ml; thiamindiphosphate--5.06 micrograms/100 ml activity of transketolase was 11.59 +/- 0.23 mmol/l. The "TDP" -effect was altered from 4% to 12%. In blood of oncological patients the concentration of total thiamin was 4.47 +/- 0.35 micrograms/100 ml and that of thiamindiphosphate 3.09 +/- 0.27 micrograms/100 ml, i.e. they were decreased by 40%. The transketolase activity was decreased by 20% (9.40 +/- 0.37 mmol/l); the "TDP" -effect was altered from 5% to 42%.
Download PDF:
Reference: Trebukhina R.V., Tumanov V.N., Avdeĭchik L.A., Bobko I.N., Tsabenko I.I., Transketolase activity and thiamine diphosphate content in oncological patients, Voprosy meditsinskoi khimii, 1983, vol: 29(5), 100-103.
References
 1985(Vol:31)
 1984(Vol:30)
 1983(Vol:29)
 1982(Vol:28)
 1981(Vol:27)
 1980(Vol:26)
 1979(Vol:25)
 1978(Vol:24)
 1977(Vol:23)
 1976(Vol:22)