Voprosy meditsinskoi khimii (ISSN 0042-8809)

Hormonal regulation of superoxide dismutase turnover in rat liver

   
Komov V.P., Ivanova E.Yu.
PubMed Id: 6359678
Year: 1983 vol: 29  issue:5  pages: 79-82
Abstract: Insulin inhibited and glucagon stimulated degradation and biosynthesis of superoxide dismutase (SOD) in cytosol and mitochondrial fractions of rat liver tissue. At the same time, insulin increased turnover of SOD in motochondria. Hormones, administered into the animals, and the hormones secretion of which was stimulated by means of high doses of glucose (endogenous insulin) and of arginine (endogenous glucagon), affected dissimilarly the synthesis and degradation of individual enzymatic forms of SOD.
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Reference: Komov V.P., Ivanova E.Yu., Hormonal regulation of superoxide dismutase turnover in rat liver, Voprosy meditsinskoi khimii, 1983, vol: 29(5), 79-82.
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