Voprosy meditsinskoi khimii (ISSN 0042-8809)

Phospholipids in the liver and brain of animals in acute oxythiamine-induced avitaminosis B1

   
Pavlenia A.K., Ostrovskiĭ I.M., Larin F.S.
PubMed Id: 6670222
Year: 1983 vol: 29  issue:6  pages: 73-76
Abstract: Under conditions of acute avitaminosis BI caused by hydroxythiamine administration, the amount of phosphatidyl ethanolamine was increased in animal liver tissue with simultaneous elevation of stearic and arachidonic fatty acids in the phospholipid. Incorporation of 2-14C-acetate into phosphatidyl choline and phosphatidyl ethanolamine as well as into their fatty acid residues was increased and incorporation of 2-14C-pyruvate--into phosphatidyl ethanolamine and its glycerol fragment was also increased. The content of these phospholipid fractions as well as incorporation of 2-14C-acetate and 2-14C-pyruvate into their structure were unaltered in rat brain tissue.
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Reference: Pavlenia A.K., Ostrovskiĭ I.M., Larin F.S., Phospholipids in the liver and brain of animals in acute oxythiamine-induced avitaminosis B1, Voprosy meditsinskoi khimii, 1983, vol: 29(6), 73-76.
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