Voprosy meditsinskoi khimii (ISSN 0042-8809)

Determination of the ratio of membrane-bound and free polyribosomes and of the content of thyroglobulin in these fractions in normal thyroid gland cells and in several types of thyroid diseases

   
Atakhanova B.A., Kadyrova D.A., Turakulov Ia.Kh., Il'iasov Sh.Sh.
PubMed Id: 6710934
Year: 1984 vol: 30  issue:1  pages: 32-34
Abstract: The ratio of membrane-bound and free polyribosomes in thyroid gland cells was decreased two-fold in nodular euthyroid goiter and five-fold--in Hashimoto thyroiditis; a slight increase in thyroglobulin synthesis in free polyribosomes was noted in goiter. Impairments in transfer of the translation products across membranes of rough endoplasmic reticulum may be one of the causes of deteriorations in thyroglobulin synthesis in goiters.
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Reference: Atakhanova B.A., Kadyrova D.A., Turakulov Ia.Kh., Il'iasov Sh.Sh., Determination of the ratio of membrane-bound and free polyribosomes and of the content of thyroglobulin in these fractions in normal thyroid gland cells and in several types of thyroid diseases, Voprosy meditsinskoi khimii, 1984, vol: 30(1), 32-34.
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