Voprosy meditsinskoi khimii (ISSN 0042-8809)

Antitryptic and antichymotryptic activity of salivary gland secretions and intestinal contents of the medical leech Hirudo medicinalis

   
Baskova I.P., Mosolov V.V., Nikonov G.I., Cherkesova D.U.
PubMed Id: 6546826
Year: 1984 vol: 30  issue:1  pages: 64-66
Abstract: Antithrombin, antitryptic and antichymotryptic activities were studied in various tissues of medical leech Hirudo medicinalis. Maximal antithrombin and antitryptic activities were found in secretion products of salivary glands. Intestinal chyme exhibited distinct antichymotryptic activity. The antichymotrypsin activity correlated with antithrombin activity in hirudin preparations, obtained after isoelectrofocusing and free of bdellines. A preparation of "pseudohirudin" exhibited neither antitryptic nor antichymotryptic activities.
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Reference: Baskova I.P., Mosolov V.V., Nikonov G.I., Cherkesova D.U., Antitryptic and antichymotryptic activity of salivary gland secretions and intestinal contents of the medical leech Hirudo medicinalis, Voprosy meditsinskoi khimii, 1984, vol: 30(1), 64-66.
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