Urinary excretion of toxic peptides in patients with thermal burns | 
 
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| Salomatin V.V., Lifshits R.I. | | PubMed Id: 6474936 | | Year: 1984 vol: 30 issue:3 pages: 120-124 | | Abstract: A fraction of toxic ninhydrin-positive substances was isolated from urine of healthy persons and of the patients with acute burn toxemia using a multi-step technique, which involved ion exchange chromatography on Dowex resins, gel filtration on Sephadex G-15 and ultrafiltration on Diaflo UM-0.5. The daily excretion of the substances was about 4-fold higher in the patients as compared with healthy persons. The fraction contained basic peptides with molecular masses of 500-2,000 daltons. The total toxicity of these peptide was higher by an order of magnitude in the patients with burns as compared with healthy persons. | | Download PDF: | | Reference: Salomatin V.V., Lifshits R.I., Urinary excretion of toxic peptides in patients with thermal burns, Voprosy meditsinskoi khimii, 1984, vol: 30(3), 120-124. | |
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