Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of a purine-free diet on the purine phosphoribosyltransferase activity of erythrocytes in patients with Lesch-Nyhan syndrome

   
Semenova I.A., Pen'kovskaia N.P.
PubMed Id: 6506590
Year: 1984 vol: 30  issue:4  pages: 94-97
Abstract: Activity of purine phosphoribosyl transferases was studied in 11 patients with Lesch-Nyhan syndrome before and within 1 or 3 months after beginning of the purine-free diet treatment. The enzymatic activity tended to normalization within 1 month after the dietary treatment but the ratio of the enzymes activity was deteriorated within the subsequent 3 months of treatment. A positive clinical effect of the purine-free diet was noted.
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Reference: Semenova I.A., Pen'kovskaia N.P., Effect of a purine-free diet on the purine phosphoribosyltransferase activity of erythrocytes in patients with Lesch-Nyhan syndrome, Voprosy meditsinskoi khimii, 1984, vol: 30(4), 94-97.
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