Voprosy meditsinskoi khimii (ISSN 0042-8809)

Lipid metabolism of the heart in ischemia and postischemic reperfusion

   
Toleĭkis A.I., Dagis A.I., Trumpitskas A.Yu., Prashkiavichius A.K.
PubMed Id: 4002648
Year: 1985 vol: 31  issue:2  pages: 102-105
Abstract: Content of unesterified fatty acids (FFA), phospholipids and triglycerides was studied in myocardium of control rabbits, of rabbits with ischemia (1 hr and 4 hrs) of myocardium and in postischemic reperfusion. In the ischemic myocardium content of phospholipids was gradually decreased; FFA increased within the first hour of ischemia. In reperfusion and prolongation of ischemia up to 4 hrs FFA were not altered. The data obtained suggest that a decrease in the ratio between the rates of FFA consumption and of lipid hydrolysis was responsible for an increase in the FFA content and in the phospholipid concentration.
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Reference: Toleĭkis A.I., Dagis A.I., Trumpitskas A.Yu., Prashkiavichius A.K., Lipid metabolism of the heart in ischemia and postischemic reperfusion, Voprosy meditsinskoi khimii, 1985, vol: 31(2), 102-105.
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