Voprosy meditsinskoi khimii (ISSN 0042-8809)

Prevention of impairment of myocardium metabolism and function in immobilization stress using previous adaptation to short stress exposures

   
Meerson F.Z., Dolgikh V.T., Smolentseva V.N., Batrachenko E.R.
PubMed Id: 4040677
Year: 1985 vol: 31  issue:3  pages: 41-45
Abstract: A long-term immobilization stress was shown to cause a distinct enzymemia in rats. Simultaneously, activation of lipid peroxidation and a decrease in glycogen content were observed in myocardium; a distinctly increased penetration of aspartate transferase, lactate- and malate dehydrogenases and RNAase into coronary circulation was found in isolated heart of the animals. These impairments of metabolism were accompanied by a depression of the heart contractile function. The impairments in metabolism and in heart functions might be prevented by preadaptation of the animals to multiple short-term immobilization effects, which did not cause any impairments per se.
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Reference: Meerson F.Z., Dolgikh V.T., Smolentseva V.N., Batrachenko E.R., Prevention of impairment of myocardium metabolism and function in immobilization stress using previous adaptation to short stress exposures, Voprosy meditsinskoi khimii, 1985, vol: 31(3), 41-45.
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