Voprosy meditsinskoi khimii (ISSN 0042-8809)

Mechanism of impairment of energy metabolism in respiratory muscles in experimental botulism

   
Morrison V.V.
PubMed Id: 4024533
Year: 1985 vol: 31  issue:3  pages: 64-67
Abstract: Phase alterations in content of adenylic nucleotides were observed in muscular and nervous tissues in dynamics of botulinic intoxication in rats. Experiments with administration of 4-aminopyridine and alpha-tocopherol showed that a decreased rate of mediator liberation in cholinergic synapses and activation of lipid peroxidation were apparently responsible for impairments in energy metabolism.
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Reference: Morrison V.V., Mechanism of impairment of energy metabolism in respiratory muscles in experimental botulism, Voprosy meditsinskoi khimii, 1985, vol: 31(3), 64-67.
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