Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of changes in the oxygen level on cholesterol esterase activity of the liver of intact rats and rats subjected to chronic hypoxia

   
Morozova I.Yu., Morozov A.V., Dushkin M.I., Dolgov A.V., Medvedeva I.N.
PubMed Id: 4090388
Year: 1985 vol: 31  issue:6  pages: 60-62
Abstract: Alterations in activity of cholesterol esterases from lysosomal, microsomal and cytoplasmic cell fractions of rat liver tissue were studied under conditions of acute and chronic hypoxia and hyperoxia. Activity of the membrane-bound lysosomal and microsomal cholesterol esterases was decreased but the cytoplasmic enzyme was activated in acute hypoxia and hyperoxia. These data suggest that the enzymes, responsible for alterations in the ratio free cholesterol/cholesterol esters in cells, are dependent on the level of oxygen consumption.
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Reference: Morozova I.Yu., Morozov A.V., Dushkin M.I., Dolgov A.V., Medvedeva I.N., Effect of changes in the oxygen level on cholesterol esterase activity of the liver of intact rats and rats subjected to chronic hypoxia, Voprosy meditsinskoi khimii, 1985, vol: 31(6), 60-62.
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