Voprosy meditsinskoi khimii (ISSN 0042-8809)

Age-dependent characteristics of the effect of insulin on 5'-nucleotidase activity in liver plasma membranes

   
Iakubovskiĭ S.M., Gatsko G.G.
PubMed Id: 3004038
Year: 1985 vol: 31  issue:6  pages: 63-64
Abstract: Vmax of 5'-nucleotidase was found to be similar in liver plasmatic membranes of both 4-5 months old male rats and 24-26 months old animals. At the same time, Km value was higher in the membranes of old rats than in young animals. Insulin (administered at a dose of 2 un per 100 g of body mass) increased the enzyme Vmax without some age-dependent differences and decreased Km value in old animals as compared with controls.
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Reference: Iakubovskiĭ S.M., Gatsko G.G., Age-dependent characteristics of the effect of insulin on 5'-nucleotidase activity in liver plasma membranes, Voprosy meditsinskoi khimii, 1985, vol: 31(6), 63-64.
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