Voprosy meditsinskoi khimii (ISSN 0042-8809)

Desensitization with acetylsalicylate and salicylate of fructose-1,6-diphosphatase from the rabbit liver and skeletal muscles to allosteric inhibition of AMP

   
Beliaeva N.F., Glinka E.Yu., Nikulin I.R., Kagan Z.S.
PubMed Id: 3010569
Year: 1986 vol: 32  issue:2  pages: 50-53
Abstract: Acetylsalicylate and salicylate partially desensitized fructose 1,6-biphosphatase from rabbit liver and skeletal muscle to allosteric AMP inhibition. The desensitization was accompanied by a decrease in cooperativity between allosteric sites especially distinct for the liver isoenzyme. The effect of salicylate on both isoenzymes was more pronounced than that of acetylsalicylate. No essential differences in the effect of the compounds studied on these isoenzymes were found.
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Reference: Beliaeva N.F., Glinka E.Yu., Nikulin I.R., Kagan Z.S., Desensitization with acetylsalicylate and salicylate of fructose-1,6-diphosphatase from the rabbit liver and skeletal muscles to allosteric inhibition of AMP, Voprosy meditsinskoi khimii, 1986, vol: 32(2), 50-53.
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