Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of enterosorption on EPR signals in the liver of rats of different ages

   
Frol'kis V.V., Kol'tover V.K., Gorban' E.N., Paramonova G.I., Shcherbitskaia E.V.
PubMed Id: 3014740
Year: 1986 vol: 32  issue:3  pages: 79-81
Abstract: Liver EPR signals were studied in adult (8 months) and old (24 months) Wistar male rats after the 30 days course of enterosorption carried out daily. The signals were analyzed at the values of g = 1.94, 2.00, 2.25, 2.035, 2.16, 2.10 and 1.97. Age-dependent differences were found in liver EPR signals of intact animals, i. e. the intensity of signals of g = 1.97, 2.00, 1.97 and 2.25 was decreased in old animals. In adult animals enterosorption caused a decrease of signals of g = 2.25, 1.94, 2.00, 2.16 and 2.10. In old animals the treatment led to a dissimilar effect: the intensity of signals was decreased at the ranges of g = 2.25, distinctly increased at g = 1.97 and unaltered at the other EPR signal values studied. Geroprotective action of enterosorption is discussed considering the decrease in enzymatic activity of electron transport systems due to the treatment studied.
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Reference: Frol'kis V.V., Kol'tover V.K., Gorban' E.N., Paramonova G.I., Shcherbitskaia E.V., Effect of enterosorption on EPR signals in the liver of rats of different ages, Voprosy meditsinskoi khimii, 1986, vol: 32(3), 79-81.
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