Voprosy meditsinskoi khimii (ISSN 0042-8809)

Characteristic features of 35S-benzoylthiamine monophosphate in albino mice

   
Karpov L.M., Rozanov A.Ya., Filippova T.O.
PubMed Id: 3765492
Year: 1986 vol: 32  issue:4  pages: 136-139
Abstract: Equimolar doses (30 mM/kg) of 35S-labelled thiamin, thiamin monophosphate or benzoyl thiamin monophosphate were administered intraperitoneally into mice. Increase in content of labelled metabolites, derived from 35S-benzoyl thiamin monophosphate, as compared with 35S-thiamin and 35S-thiamin monophosphate, was more distinct and prolonged in mice tissues, especially in brain and heart muscle, within 6-24 hrs. In blood this relationship was opposite. Total 35S was excreted with urine also at the highest rate after the 35S-benzoyl thiamin monophosphate administration as compared with the effect of thiamin and thiamin monophosphate but differences between the experimental data obtained with the latter compounds were only slight.
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Reference: Karpov L.M., Rozanov A.Ya., Filippova T.O., Characteristic features of 35S-benzoylthiamine monophosphate in albino mice, Voprosy meditsinskoi khimii, 1986, vol: 32(4), 136-139.
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