Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of lipid peroxidation on the Mg-ATPase activity of the brain and liver

   
Lunets E.F., Kuchuro S.V., Kostiuk V.A.
PubMed Id: 2945317
Year: 1986 vol: 32  issue:4  pages: 32-35
Abstract: Effect of ascorbate-dependent lipid peroxidation on activity of Mg2+-ATPase was studied in rat brain and liver tissues. Lipid peroxidation was shown to inactivate Mg2+-ATPase in the fraction of "heavy" brain microsomes. The rate of inactivation was directly related to the amount of the primary products of lipid peroxidation, accumulating in membrane lipids. At the same time, more intensive lipid peroxidation, as evidenced by content of diene conjugates and malonic dialdehyde, did not affect the liver Mg2+-ATPase.
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Reference: Lunets E.F., Kuchuro S.V., Kostiuk V.A., Effect of lipid peroxidation on the Mg-ATPase activity of the brain and liver, Voprosy meditsinskoi khimii, 1986, vol: 32(4), 32-35.
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