Voprosy meditsinskoi khimii (ISSN 0042-8809)

Biochemical and ultrastructural changes in animal brain after intracisternal administration of the cerebrospinal fluid from patients with schizophrenia

   
Vilkov G.A., Trapezontseva R.A., Siletskii O.Ia., Bardakhch'ian E.A., Minoranskaia A.P.
PubMed Id: 3532532
Year: 1986 vol: 32  issue:4  pages: 91-93
Abstract: After intracisternal administration of liquor from patients with schizophrenia into rabbits and rats content of catecholamines, gangliosides and cerebrosides was decreased, while acid proteinase was activated in brain tissue. At the same time, ultrastructural impairments occurred in nervous cells. These data suggest that cytotoxic antibrain antibodies are present in liquor of schizophrenic patients.
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Reference: Vilkov G.A., Trapezontseva R.A., Siletskii O.Ia., Bardakhch'ian E.A., Minoranskaia A.P., Biochemical and ultrastructural changes in animal brain after intracisternal administration of the cerebrospinal fluid from patients with schizophrenia, Voprosy meditsinskoi khimii, 1986, vol: 32(4), 91-93.
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