Voprosy meditsinskoi khimii (ISSN 0042-8809)

Comparative study of the effect of ecdysterone, turkesterone and nerobol on the function of rat liver mitochondria in experimental diabetes

   
Tashmukhamedova M.A., Almatov K.T., Syrov V.N., Sultanov M.B., Abidov A.A.
PubMed Id: 3776112
Year: 1986 vol: 32  issue:5  pages: 24-28
Abstract: Oxidative phosphorylation and Ca2+-transport functions of liver mitochondria were normalized in rats with alloxane diabetes after peroral administration of phytoecdisteroids - ecdisterone and turkesterone (5 mg/kg) or nerobol (10 mg/kg) within 15 days. These drugs normalized the activity of NADH dehydrogenase and succinate dehydrogenase in respiratory chain of mitochondria, increased distinctly stability of the enzymes to the effect of such factors as heating, effect of phospholipase A2 or trypsin.
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Reference: Tashmukhamedova M.A., Almatov K.T., Syrov V.N., Sultanov M.B., Abidov A.A., Comparative study of the effect of ecdysterone, turkesterone and nerobol on the function of rat liver mitochondria in experimental diabetes, Voprosy meditsinskoi khimii, 1986, vol: 32(5), 24-28.
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