Voprosy meditsinskoi khimii (ISSN 0042-8809)

Characteristics of lipid composition, lipid peroxidation intensity and ATPase activity of lymphocytes in children with acute respiratory viral infections

   
Ivanova V.V., Govorova L.V., Gudieva N.B., Lukina V.V., Bulovskaia L.N.
PubMed Id: 2949430
Year: 1986 vol: 32  issue:6  pages: 111-115
Abstract: Content of total lipids, intensity of lipid peroxidation and activity of ATPases were studied in lymphocytes of children with acute respiratory-viral infection (ARVI). Decrease in the content of total lipids correlated with lipid peroxidation in ARVI. At the same time, a decrease in the activity of ATPases occurred due to a decrease in the content of total lipids and alteration in the phospholipid composition of lymphocyte membranes. At the period of convalescence the patterns studied tended to normalization only in children with non-complicated forms of ARVI. Active and slowly-developed lipid peroxidation in lymphocytes of various children groups suggest dissimilar alterations in the structure and composition of the cellular membranes, which increases our knowledge on pathogenesis of ARVI.
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Reference: Ivanova V.V., Govorova L.V., Gudieva N.B., Lukina V.V., Bulovskaia L.N., Characteristics of lipid composition, lipid peroxidation intensity and ATPase activity of lymphocytes in children with acute respiratory viral infections, Voprosy meditsinskoi khimii, 1986, vol: 32(6), 111-115.
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