Voprosy meditsinskoi khimii (ISSN 0042-8809)

Characteristics of an experimental model of alcoholic cardiomyopathy by diagnostic enzyme tests

   
Antonenkov V.D., Popova S.V., Pirozhkov S.V., Krasnova S.N.
PubMed Id: 3811274
Year: 1986 vol: 32  issue:6  pages: 115-118
Abstract: Experimental alcoholic cardiomyopathy was simulated by aminotriazole administration (1 g/kg) into chronically ethanol intoxicated rats. Activity and isozyme spectra of organospecific enzymes and bilirubin concentration were determined in blood plasma. Activity of catalase was assayed in liver and heart homogenates. The data obtained suggest that not only myocardium but also skeletal muscles were impaired in the experimental group of animals. This phenomenon appears to elucidate the similar pathological effect of ethyl alcohol on myocardium and skeletal muscles.
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Reference: Antonenkov V.D., Popova S.V., Pirozhkov S.V., Krasnova S.N., Characteristics of an experimental model of alcoholic cardiomyopathy by diagnostic enzyme tests, Voprosy meditsinskoi khimii, 1986, vol: 32(6), 115-118.
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