Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of vitamin E deficiency on creatine phosphokinase activity and creatine phosphate levels in the heart muscle

   
Golubeva L.Yu., Dzhaparidze L.M.
PubMed Id: 3811276
Year: 1986 vol: 32  issue:6  pages: 121-122
Abstract: Vitamin E deficient diet of rats developed impairments in energy metabolism of myocardium, involving a decrease in content of creatine phosphate and in the activity of creatine phosphokinase by 20-35%. Concentration of adenine nucleotides was not altered in myocardium and the content of glycogen was only slightly changed. The impairments in activity of creatine phosphokinase and in the content of creatine phosphate might be among the factors responsible for deterioration of the heart muscle contractile functions in avitaminosis E.
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Reference: Golubeva L.Yu., Dzhaparidze L.M., Effect of vitamin E deficiency on creatine phosphokinase activity and creatine phosphate levels in the heart muscle, Voprosy meditsinskoi khimii, 1986, vol: 32(6), 121-122.
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