Voprosy meditsinskoi khimii (ISSN 0042-8809)

Age-related characteristics of thymidine metabolism in healthy subjects and in patients with stomach ulcer and cancer

   
Borzenko V.G., Gorbachev A.A., Dumanskiĭ I.V., Orlova S.M., Shevchenko V.V.
PubMed Id: 3811286
Year: 1986 vol: 32  issue:6  pages: 52-54
Abstract: Biosynthesis of pyrimidine nucleotides was intensified in proliferating tissues. Age-dependent alterations in activities of thymidine kinase and thymidine phosphorylase were found in healthy persons of 17-70 years old. Distinct increase in activity of thymidine kinase was observed in patients with gastric ulcer but the activity was decreased with ageing. Alterations in the ratio between anabolic and catabolic reactions involving thymidine were studied also in patients with gastric tumor depending on age.
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Reference: Borzenko V.G., Gorbachev A.A., Dumanskiĭ I.V., Orlova S.M., Shevchenko V.V., Age-related characteristics of thymidine metabolism in healthy subjects and in patients with stomach ulcer and cancer, Voprosy meditsinskoi khimii, 1986, vol: 32(6), 52-54.
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