Voprosy meditsinskoi khimii (ISSN 0042-8809)

Modification of the mitochondrial membrane from the rat liver by synthetic phospholipids

   
Tat'ianenko L.V., Sokolova N.M., Mashkovskii Iu.Sh.
PubMed Id: 3811297
Year: 1986 vol: 32  issue:6  pages: 86-89
Abstract: Reconstruction of rat liver mitochondrial membrane by means of synthetic phospholipids enabled to improve the conception on the role of lipids in formation of monoamine oxidase multiple forms as well as elucidated the functions of mitochondrial membrane itself, which contains a tightly-mounted MAO, in regulation of biogenic amines enzymatic oxidation. The data obtained excluded the deciding importance of phospholipids in formation of two types of monoamine oxidases and corroborated the hypothesis on the active role of mitochondrial membrane in enzymatic reactions of tightly-mounted MAO as well as these data suggest that alterations in conformational mobility of the membrane hydrophobic sites shifted distinctly the kinetics of the enzymatic reaction.
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Reference: Tat'ianenko L.V., Sokolova N.M., Mashkovskii Iu.Sh., Modification of the mitochondrial membrane from the rat liver by synthetic phospholipids, Voprosy meditsinskoi khimii, 1986, vol: 32(6), 86-89.
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