Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of acid extraction on the osteogenic activity of bone tissue

   
Sumarokov D.D.
PubMed Id: 3107216
Year: 1987 vol: 33  issue:1  pages: 51-54
Abstract: Rat bones demineralized in HCl and TCA exhibited distinct osteoinductive activity while the bones demineralized using EDTA did not show the activity. HCl- and TCA-extracts of bones differed from EDTA extracts by chromatographic and radiochromatographic profiles. At the same time, HCl- and TCA-extracts contained additional fraction. The substances involved in the fraction appear to be responsible for inhibition of the osteoinductive factor of bone tissue.
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Reference: Sumarokov D.D., Effect of acid extraction on the osteogenic activity of bone tissue, Voprosy meditsinskoi khimii, 1987, vol: 33(1), 51-54.
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