Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of emotional stress on the activity of enzymes of glutathione metabolism

   
Kolesnichenko L.S., Mantorova N.S., Shapiro L.A., Ol'khovskii I.A., Baron A.V.
PubMed Id: 2820145
Year: 1987 vol: 33  issue:3  pages: 85-88
Abstract: Emotional stress during 20 min induced the stimulation of the glutathione peroxidase activity in heart, liver and kidney tissues and the activation of glutathione-S-transferase in heart and liver tissues. gamma-Glutamyl transferase activity was inhibited in liver and kidney tissues. The alterations were gradually decreased in heart greater than or equal to liver greater than kidney. Both catecholamines (in vivo) and cAMP (in vitro) produced the same effects. Close correlation between the stress and cAMP actions on the glutathione metabolizing enzymes was found. No changes of glutathione reductase activity was observed in all the tissues studied.
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Reference: Kolesnichenko L.S., Mantorova N.S., Shapiro L.A., Ol'khovskii I.A., Baron A.V., Effect of emotional stress on the activity of enzymes of glutathione metabolism, Voprosy meditsinskoi khimii, 1987, vol: 33(3), 85-88.
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