Voprosy meditsinskoi khimii (ISSN 0042-8809)

Complex formation of heparin with the inhibitor of non-enzymatic fibrinolysis isolated from the spleen

   
Liapina L.A., Ammosova I.M.
PubMed Id: 3630024
Year: 1987 vol: 33  issue:3  pages: 88-91
Abstract: Formation of complexes between heparin and protein inhibitor of non-enzymatic fibrinolysis, isolated from spleen tissue of healthy animals, was demonstrated by means of cross electrophoresis, UV- and IR-spectrophotometries. Suppression of the spleen inhibitor activity towards non-enzymatic fibrinolysis occurred via its complex-formation with heparin, where the inhibitor aminogroups reacted with sulfo- or carboxyl groups of heparin.
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Reference: Liapina L.A., Ammosova I.M., Complex formation of heparin with the inhibitor of non-enzymatic fibrinolysis isolated from the spleen, Voprosy meditsinskoi khimii, 1987, vol: 33(3), 88-91.
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