Voprosy meditsinskoi khimii (ISSN 0042-8809)

Changes in the microviscosity of the plasma membrane and sensitivity to PGE1 of platelets stored at 22 and 4 degrees C

   
Kuznetsov V.A., Melkonian S.G., Lisovskaia I.L., Volkova R.I.
PubMed Id: 2821694
Year: 1987 vol: 33  issue:4  pages: 28-31
Abstract: Effect of platelet storage within 1-3 days on the cell membranes microviscosity, studied by means of a spin probe, and their sensitivity to PGEI, inhibitor of ADP aggregation, were studied. The highest values of fluidity and PGEI sensitivity exhibited plasmatic membranes of platelets stored at 22 degrees; lower values were found in the membranes stored at 4 degrees as compared with native fresh platelets. The data obtained suggest the dissimilar character of alterations in structure and functions of platelet plasmatic membrane during storage at 22 degrees and 4 degrees.
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Reference: Kuznetsov V.A., Melkonian S.G., Lisovskaia I.L., Volkova R.I., Changes in the microviscosity of the plasma membrane and sensitivity to PGE1 of platelets stored at 22 and 4 degrees C, Voprosy meditsinskoi khimii, 1987, vol: 33(4), 28-31.
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