Voprosy meditsinskoi khimii (ISSN 0042-8809)

Na,K-ATPase activity of erythrocyte ghosts of mammals in the presence of alamethicin and p-nitrophenylphosphate

   
Sokol'nikov A.A., Kodentsova V.M., Gulidova G.P., Mironova G.D.
PubMed Id: 2840771
Year: 1988 vol: 34  issue:2  pages: 53-56
Abstract: After preincubation of erythrocyte ghosts isolated from Sprague-Dawley rats activity of Na, K-ATPase was more successfully manifested, being elevated about 2.5-fold, while the ratio Mg-ATPase/Na, K-ATPase was decreased 3-fold. Optimal ratio of alamethicin/protein was equal to 0.3. The similar results were obtained if p-nitrophenyl phosphate, easily penetrating through the erythrocyte membrane, was used as an exogenous substrate.
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Reference: Sokol'nikov A.A., Kodentsova V.M., Gulidova G.P., Mironova G.D., Na,K-ATPase activity of erythrocyte ghosts of mammals in the presence of alamethicin and p-nitrophenylphosphate, Voprosy meditsinskoi khimii, 1988, vol: 34(2), 53-56.
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