Voprosy meditsinskoi khimii (ISSN 0042-8809)

Biological activity of tRNA and aminoacyl-tRNA-synthetases from the swine myocardium in anoxia and subsequent reoxygenation

   
Kashauskas A.P., Tamuliavichius A.A., Lukoshiavichius L.Yu., Ivanov L.L., Prashkiavichius A.K.
PubMed Id: 3400198
Year: 1988 vol: 34  issue:2  pages: 84-86
Abstract: Distinct decrease in the rate of aminoacylation of tRNAs, specific to alanine, glutamic acid, leucine and serine, was found after 20 min anoxia of perfused pig heart. In the anoxia activity of aminoacyl-tRNA synthetases of the same amino acid specificity was increased. Reduction of these macromolecules activity was observed in reoxygenation of the anoxic myocardium. Biological activity of tRNA and aminoacyl-tRNA synthetases in pig myocardium appears to depend on the supply of heart with oxygen.
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Reference: Kashauskas A.P., Tamuliavichius A.A., Lukoshiavichius L.Yu., Ivanov L.L., Prashkiavichius A.K., Biological activity of tRNA and aminoacyl-tRNA-synthetases from the swine myocardium in anoxia and subsequent reoxygenation, Voprosy meditsinskoi khimii, 1988, vol: 34(2), 84-86.
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