Voprosy meditsinskoi khimii (ISSN 0042-8809)

Changes in the cyclic nucleotide system during experimental burns in immature rats

   
Davletov E.G., Karelin A.A., Kamilov F.Kh.
PubMed Id: 2844018
Year: 1988 vol: 34  issue:3  pages: 120-124
Abstract: Thermal trauma caused a distinct increase in content of cAMP and cGMP in blood as well as in liver and kidney tissues of one-month-old rats within the first week after burns. Alterations, which depend on the step of burn development, were found in basal and adrenaline, fluoride-stimulated activities of adenylate cyclase in liver and kidney tissues of experimental animals. Activity of phosphodiesterase was altered only slightly under similar experimental conditions while pronounced decrease in the enzymatic activity was observed in rat liver tissue within 6 hrs after burns.
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Reference: Davletov E.G., Karelin A.A., Kamilov F.Kh., Changes in the cyclic nucleotide system during experimental burns in immature rats, Voprosy meditsinskoi khimii, 1988, vol: 34(3), 120-124.
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